Nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine
Lidocaine (LDC) is a local anesthetic that can be used for post-surgical or cancer related pain, via intravenous infusion or bolus. An alternative to maintain drug plasma levels are the sustained release carriers, whereas nanostructured lipid carriers (NLCs) stand out; they have biocompatibility, lo...
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| Format: | Online |
| Language: | Portuguese |
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Universidade Estadual de Campinas
2018
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| Online Access: | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/110 |
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| author | Pelegrine, Ana Carolina Martins Nascimento, Laura de Oliveira Araújo, Viviane Lucia Beraldo de |
| author_facet | Pelegrine, Ana Carolina Martins Nascimento, Laura de Oliveira Araújo, Viviane Lucia Beraldo de |
| author_sort | Pelegrine, Ana Carolina Martins |
| collection | Portal de Eventos Científicos da UNICAMP |
| container_reference | Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp |
| description | Lidocaine (LDC) is a local anesthetic that can be used for post-surgical or cancer related pain, via intravenous infusion or bolus. An alternative to maintain drug plasma levels are the sustained release carriers, whereas nanostructured lipid carriers (NLCs) stand out; they have biocompatibility, low toxicity, reproducibility and high efficiency in the transport of hydrophobic drugs.This work aims to study the solubility parameter of the LDC pre formulation in several ultra-purified lipids, compatible with the endovenous route, and to formulate NLCs based on these lipids for LDC encapsulation. |
| first_indexed | 2025-10-08T13:49:30Z |
| format | Online |
| id | ojs-article-110 |
| institution | Universidade Estadual de Campinas |
| issn | 2596-1969 |
| language | por |
| last_indexed | 2025-10-08T13:49:30Z |
| publishDate | 2018 |
| publisher | Universidade Estadual de Campinas |
| record_format | ojs |
| spelling | ojs-article-1102025-09-26T14:32:30Z Nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine Pelegrine, Ana Carolina Martins Nascimento, Laura de Oliveira Araújo, Viviane Lucia Beraldo de Lidocaine Intravenous Lipids nanocarriers. Lidocaine (LDC) is a local anesthetic that can be used for post-surgical or cancer related pain, via intravenous infusion or bolus. An alternative to maintain drug plasma levels are the sustained release carriers, whereas nanostructured lipid carriers (NLCs) stand out; they have biocompatibility, low toxicity, reproducibility and high efficiency in the transport of hydrophobic drugs.This work aims to study the solubility parameter of the LDC pre formulation in several ultra-purified lipids, compatible with the endovenous route, and to formulate NLCs based on these lipids for LDC encapsulation. Universidade Estadual de Campinas 2018-12-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/110 10.20396/revpibic262018110 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp 2596-1969 por https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/110/104 Copyright (c) 2018 Ana Carolina Martins Pelegrine, Laura de Oliveira Nascimento http://creativecommons.org/licenses/by/4.0 |
| spellingShingle | Pelegrine, Ana Carolina Martins Nascimento, Laura de Oliveira Araújo, Viviane Lucia Beraldo de Lidocaine Intravenous Lipids nanocarriers. Nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine |
| title | Nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine |
| title_full | Nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine |
| title_fullStr | Nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine |
| title_full_unstemmed | Nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine |
| title_short | Nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine |
| title_sort | nanostructured lipid carriers with ultra purified lipids for sustained release of intravenous lidocaine |
| topic | Lidocaine Intravenous Lipids nanocarriers. |
| url | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/110 |
| work_keys_str_mv | AT pelegrineanacarolinamartins nanostructuredlipidcarrierswithultrapurifiedlipidsforsustainedreleaseofintravenouslidocaine AT nascimentolauradeoliveira nanostructuredlipidcarrierswithultrapurifiedlipidsforsustainedreleaseofintravenouslidocaine AT araujovivianeluciaberaldode nanostructuredlipidcarrierswithultrapurifiedlipidsforsustainedreleaseofintravenouslidocaine |
