Investigation of changes in the expression of human blood plasma proteins in major depressive disorder patients associated to an effective antidepressant response
Major depressive disorder is a complex multi-factor psychiatric disorder whose consequences can be debilitating, being one of the main worldwide causes of suicide. Its treatment is predominantly antidepressants and regular counseling and despite the treatment’s effectiveness, 10-30% of the patients...
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| Format: | Online |
| Language: | English |
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Universidade Estadual de Campinas
2019
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| Online Access: | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1109 |
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| author | Carlson, Pâmela Tavares Souza, Daniel Martins de Costa, Licia C. Silva |
| author_facet | Carlson, Pâmela Tavares Souza, Daniel Martins de Costa, Licia C. Silva |
| author_sort | Carlson, Pâmela Tavares |
| collection | Portal de Eventos Científicos da UNICAMP |
| container_reference | Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp |
| description | Major depressive disorder is a complex multi-factor psychiatric disorder whose consequences can be debilitating, being one of the main worldwide causes of suicide. Its treatment is predominantly antidepressants and regular counseling and despite the treatment’s effectiveness, 10-30% of the patients respond differently and present adverse reactions to it, which can lead to the a change in the medication used. Due to this, it is important to understand what differs in patient’s blood plasma protein that can help identify good and bad responders to treatment. Through the analysis of differential expressed protein in good responders, it is possible to investigate which biochemical processes vary between them and therefore predict possible responses to better adapt patient’s treatment. |
| first_indexed | 2025-10-08T13:53:20Z |
| format | Online |
| id | ojs-article-1109 |
| institution | Universidade Estadual de Campinas |
| issn | 2596-1969 |
| language | eng |
| last_indexed | 2025-10-08T13:53:20Z |
| publishDate | 2019 |
| publisher | Universidade Estadual de Campinas |
| record_format | ojs |
| spelling | ojs-article-11092025-09-26T14:32:30Z Investigation of changes in the expression of human blood plasma proteins in major depressive disorder patients associated to an effective antidepressant response Carlson, Pâmela Tavares Souza, Daniel Martins de Costa, Licia C. Silva Major depressive disorder Differential expression Proteomics. Major depressive disorder is a complex multi-factor psychiatric disorder whose consequences can be debilitating, being one of the main worldwide causes of suicide. Its treatment is predominantly antidepressants and regular counseling and despite the treatment’s effectiveness, 10-30% of the patients respond differently and present adverse reactions to it, which can lead to the a change in the medication used. Due to this, it is important to understand what differs in patient’s blood plasma protein that can help identify good and bad responders to treatment. Through the analysis of differential expressed protein in good responders, it is possible to investigate which biochemical processes vary between them and therefore predict possible responses to better adapt patient’s treatment. Universidade Estadual de Campinas 2019-02-14 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1109 10.20396/revpibic2620181109 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp 2596-1969 eng https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1109/1182 Copyright (c) 2019 Pâmela Tavares Carlson, Daniel Martins de Souza http://creativecommons.org/licenses/by/4.0 |
| spellingShingle | Carlson, Pâmela Tavares Souza, Daniel Martins de Costa, Licia C. Silva Major depressive disorder Differential expression Proteomics. Investigation of changes in the expression of human blood plasma proteins in major depressive disorder patients associated to an effective antidepressant response |
| title | Investigation of changes in the expression of human blood plasma proteins in major depressive disorder patients associated to an effective antidepressant response |
| title_full | Investigation of changes in the expression of human blood plasma proteins in major depressive disorder patients associated to an effective antidepressant response |
| title_fullStr | Investigation of changes in the expression of human blood plasma proteins in major depressive disorder patients associated to an effective antidepressant response |
| title_full_unstemmed | Investigation of changes in the expression of human blood plasma proteins in major depressive disorder patients associated to an effective antidepressant response |
| title_short | Investigation of changes in the expression of human blood plasma proteins in major depressive disorder patients associated to an effective antidepressant response |
| title_sort | investigation of changes in the expression of human blood plasma proteins in major depressive disorder patients associated to an effective antidepressant response |
| topic | Major depressive disorder Differential expression Proteomics. |
| url | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1109 |
| work_keys_str_mv | AT carlsonpamelatavares investigationofchangesintheexpressionofhumanbloodplasmaproteinsinmajordepressivedisorderpatientsassociatedtoaneffectiveantidepressantresponse AT souzadanielmartinsde investigationofchangesintheexpressionofhumanbloodplasmaproteinsinmajordepressivedisorderpatientsassociatedtoaneffectiveantidepressantresponse AT costaliciacsilva investigationofchangesintheexpressionofhumanbloodplasmaproteinsinmajordepressivedisorderpatientsassociatedtoaneffectiveantidepressantresponse |
