Conjugated Zn(II) complex as metallo-?-lactamase model
This work reports the synthesis, characterization and the interaction with a ?-lactam compound of a Zn(II) complex containing imidazole and pyridil groups bearing a free carboxylate for peptide conjugation. The complex was able to interact with the carboxilate next to the ?-lactam group of amoxicill...
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| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
Universidade Estadual de Campinas
2019
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| Subjects: | |
| Online Access: | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1185 |
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| Summary: | This work reports the synthesis, characterization and the interaction with a ?-lactam compound of a Zn(II) complex containing imidazole and pyridil groups bearing a free carboxylate for peptide conjugation. The complex was able to interact with the carboxilate next to the ?-lactam group of amoxicillin and the conjugation with peptide (glutathione as a model) was successful. |
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| ISSN: | 2596-1969 |
