Investigation of susceptibility to paromomycin in isolates from dogs of Leishmania (Leishmania) infantum
In Brazil, visceral leishmaniasis (VL) is a parasitic disease caused by the protozoan Leishmania (Leishmania) infantum. This disease is serious and may be lethal if not treated. The treatment of leishmaniasis in Brazil consists in the use of pentavalent antimonials and/or amphotericin B. These drugs...
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| Format: | Online |
| Language: | English |
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Universidade Estadual de Campinas
2019
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| Online Access: | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1376 |
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| author | Oliveira, Viviane da Luz Coelho, Adriano Cappellazzo Kanashiro, Edite H. Y. Rocha, Mussya C. Cotrim, Paulo C. |
| author_facet | Oliveira, Viviane da Luz Coelho, Adriano Cappellazzo Kanashiro, Edite H. Y. Rocha, Mussya C. Cotrim, Paulo C. |
| author_sort | Oliveira, Viviane da Luz |
| collection | Portal de Eventos Científicos da UNICAMP |
| container_reference | Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp |
| description | In Brazil, visceral leishmaniasis (VL) is a parasitic disease caused by the protozoan Leishmania (Leishmania) infantum. This disease is serious and may be lethal if not treated. The treatment of leishmaniasis in Brazil consists in the use of pentavalent antimonials and/or amphotericin B. These drugs are toxic, have several side effects and the effectiveness of treatment has decreased in the last years. Paromomycin is an alternative drug already used in the treatment of VL in Asia with effectiveness rate higher than 90%. In this project, we aimed to evaluate the susceptibility in vitro to paromomycin of isolates of L. (L.) infantum from dogs of the city of Embu-Guaçu, State of São Paulo. |
| first_indexed | 2025-10-08T13:54:22Z |
| format | Online |
| id | ojs-article-1376 |
| institution | Universidade Estadual de Campinas |
| issn | 2596-1969 |
| language | eng |
| last_indexed | 2025-10-08T13:54:22Z |
| publishDate | 2019 |
| publisher | Universidade Estadual de Campinas |
| record_format | ojs |
| spelling | ojs-article-13762025-09-26T14:32:30Z Investigation of susceptibility to paromomycin in isolates from dogs of Leishmania (Leishmania) infantum Oliveira, Viviane da Luz Coelho, Adriano Cappellazzo Kanashiro, Edite H. Y. Rocha, Mussya C. Cotrim, Paulo C. Visceral leishmaniasis Leishmania infantum Paromomycin Drug susceptibility. In Brazil, visceral leishmaniasis (VL) is a parasitic disease caused by the protozoan Leishmania (Leishmania) infantum. This disease is serious and may be lethal if not treated. The treatment of leishmaniasis in Brazil consists in the use of pentavalent antimonials and/or amphotericin B. These drugs are toxic, have several side effects and the effectiveness of treatment has decreased in the last years. Paromomycin is an alternative drug already used in the treatment of VL in Asia with effectiveness rate higher than 90%. In this project, we aimed to evaluate the susceptibility in vitro to paromomycin of isolates of L. (L.) infantum from dogs of the city of Embu-Guaçu, State of São Paulo. Universidade Estadual de Campinas 2019-02-19 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1376 10.20396/revpibic2620181376 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp 2596-1969 eng https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1376/1452 Copyright (c) 2019 Viviane da Luz Oliveira, Adriano Cappellazzo Coelho http://creativecommons.org/licenses/by/4.0 |
| spellingShingle | Oliveira, Viviane da Luz Coelho, Adriano Cappellazzo Kanashiro, Edite H. Y. Rocha, Mussya C. Cotrim, Paulo C. Visceral leishmaniasis Leishmania infantum Paromomycin Drug susceptibility. Investigation of susceptibility to paromomycin in isolates from dogs of Leishmania (Leishmania) infantum |
| title | Investigation of susceptibility to paromomycin in isolates from dogs of Leishmania (Leishmania) infantum |
| title_full | Investigation of susceptibility to paromomycin in isolates from dogs of Leishmania (Leishmania) infantum |
| title_fullStr | Investigation of susceptibility to paromomycin in isolates from dogs of Leishmania (Leishmania) infantum |
| title_full_unstemmed | Investigation of susceptibility to paromomycin in isolates from dogs of Leishmania (Leishmania) infantum |
| title_short | Investigation of susceptibility to paromomycin in isolates from dogs of Leishmania (Leishmania) infantum |
| title_sort | investigation of susceptibility to paromomycin in isolates from dogs of leishmania (leishmania) infantum |
| topic | Visceral leishmaniasis Leishmania infantum Paromomycin Drug susceptibility. |
| url | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1376 |
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