Functional characterization of potential antifungal agents based on molecules derived from diphenylamides on Moniliphthora perniciosa, etiological agent of cacao Witches' Broom Disease

Moniliophthora perniciosa is a fungal pathogen and causal agent of Witches' Broom Disease of cocoa (Theobroma cacao), which generates large losses for the cocoa culture. Currently, there is no effective means to control this disease, but the enzyme Alternative Oxidase (AOX) is a promissing targ...

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Main Authors: Pires, Bárbara Aliende, Pereira, Goncalo Amarante Guimaraes, Barsottini, Mario Ramos de Oliveira
Format: Online
Language:English
Published: Universidade Estadual de Campinas 2018
Subjects:
Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/180
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author Pires, Bárbara Aliende
Pereira, Goncalo Amarante Guimaraes
Barsottini, Mario Ramos de Oliveira
author_facet Pires, Bárbara Aliende
Pereira, Goncalo Amarante Guimaraes
Barsottini, Mario Ramos de Oliveira
author_sort Pires, Bárbara Aliende
collection Portal de Eventos Científicos da UNICAMP
container_reference Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp
description Moniliophthora perniciosa is a fungal pathogen and causal agent of Witches' Broom Disease of cocoa (Theobroma cacao), which generates large losses for the cocoa culture. Currently, there is no effective means to control this disease, but the enzyme Alternative Oxidase (AOX) is a promissing target for the development of novel fungicides against M. perniciosa. Here, our aim is to develop a methodology to evaluate the antifungal activity of AOX inhibitors in vitro through growth measurements of M. perniciosa in liquid culture medium.
first_indexed 2025-10-08T13:49:55Z
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institution Universidade Estadual de Campinas
issn 2596-1969
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spelling ojs-article-1802025-09-26T14:32:30Z Functional characterization of potential antifungal agents based on molecules derived from diphenylamides on Moniliphthora perniciosa, etiological agent of cacao Witches' Broom Disease Pires, Bárbara Aliende Pereira, Goncalo Amarante Guimaraes Barsottini, Mario Ramos de Oliveira Witches' Broom Disease Diphenylamides Enzyme alternative oxidase. Moniliophthora perniciosa is a fungal pathogen and causal agent of Witches' Broom Disease of cocoa (Theobroma cacao), which generates large losses for the cocoa culture. Currently, there is no effective means to control this disease, but the enzyme Alternative Oxidase (AOX) is a promissing target for the development of novel fungicides against M. perniciosa. Here, our aim is to develop a methodology to evaluate the antifungal activity of AOX inhibitors in vitro through growth measurements of M. perniciosa in liquid culture medium. Universidade Estadual de Campinas 2018-12-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/180 10.20396/revpibic262018180 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp 2596-1969 eng https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/180/154 Copyright (c) 2018 Bárbara Aliende Pires, Goncalo Amarante Guimaraes Pereira http://creativecommons.org/licenses/by/4.0
spellingShingle Pires, Bárbara Aliende
Pereira, Goncalo Amarante Guimaraes
Barsottini, Mario Ramos de Oliveira
Witches' Broom Disease
Diphenylamides
Enzyme alternative oxidase.
Functional characterization of potential antifungal agents based on molecules derived from diphenylamides on Moniliphthora perniciosa, etiological agent of cacao Witches' Broom Disease
title Functional characterization of potential antifungal agents based on molecules derived from diphenylamides on Moniliphthora perniciosa, etiological agent of cacao Witches' Broom Disease
title_full Functional characterization of potential antifungal agents based on molecules derived from diphenylamides on Moniliphthora perniciosa, etiological agent of cacao Witches' Broom Disease
title_fullStr Functional characterization of potential antifungal agents based on molecules derived from diphenylamides on Moniliphthora perniciosa, etiological agent of cacao Witches' Broom Disease
title_full_unstemmed Functional characterization of potential antifungal agents based on molecules derived from diphenylamides on Moniliphthora perniciosa, etiological agent of cacao Witches' Broom Disease
title_short Functional characterization of potential antifungal agents based on molecules derived from diphenylamides on Moniliphthora perniciosa, etiological agent of cacao Witches' Broom Disease
title_sort functional characterization of potential antifungal agents based on molecules derived from diphenylamides on moniliphthora perniciosa, etiological agent of cacao witches' broom disease
topic Witches' Broom Disease
Diphenylamides
Enzyme alternative oxidase.
url https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/180
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