When being obese is healthy: molecular evolution of genes related to metabolism in cetaceans

Energetic homeostasis is the process responsible for balancing the energy rates ingested and expelled from our organism. In most mammals, there is a strict control of the homeostasis and satiety regulation, through anorexigenic and orexigenic peptides. However, some lineages of mammals have differen...

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Main Authors: Ribeiro, Michelle, Nery, Mariana, Souza, Érica de, Ramos, Elisa
Format: Online
Language:Portuguese
Published: Universidade Estadual de Campinas 2019
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Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2235
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author Ribeiro, Michelle
Nery, Mariana
Souza, Érica de
Ramos, Elisa
author_facet Ribeiro, Michelle
Nery, Mariana
Souza, Érica de
Ramos, Elisa
author_sort Ribeiro, Michelle
collection Portal de Eventos Científicos da UNICAMP
container_reference Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 27 (2019): Congresso de Iniciação Científica UNICAMP; 1-1
description Energetic homeostasis is the process responsible for balancing the energy rates ingested and expelled from our organism. In most mammals, there is a strict control of the homeostasis and satiety regulation, through anorexigenic and orexigenic peptides. However, some lineages of mammals have different regulation, being able to not feed during months and also going through periods of intense feeding, apparently without getting satisfaction. Notorious examples of this behavior are migrating whales that perform long migrations. This project aims to investigate the genetic evolutionary story of this distinct feeding behavior, that evolved independently in some lineages. Accordingly, we investigated the evolutionary rate in genes involved in the central control of the metabolism ( POMC, MC4R, NPY ) in mammals, focusing on cetacean lineage, to better understand their evolutionary histories.
first_indexed 2025-10-08T13:56:48Z
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institution Universidade Estadual de Campinas
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spelling ojs-article-22352025-09-26T14:39:16Z When being obese is healthy: molecular evolution of genes related to metabolism in cetaceans Ribeiro, Michelle Nery, Mariana Souza, Érica de Ramos, Elisa Cetaceans Migration Evolutionary genomics Energetic homeostasis is the process responsible for balancing the energy rates ingested and expelled from our organism. In most mammals, there is a strict control of the homeostasis and satiety regulation, through anorexigenic and orexigenic peptides. However, some lineages of mammals have different regulation, being able to not feed during months and also going through periods of intense feeding, apparently without getting satisfaction. Notorious examples of this behavior are migrating whales that perform long migrations. This project aims to investigate the genetic evolutionary story of this distinct feeding behavior, that evolved independently in some lineages. Accordingly, we investigated the evolutionary rate in genes involved in the central control of the metabolism ( POMC, MC4R, NPY ) in mammals, focusing on cetacean lineage, to better understand their evolutionary histories. Universidade Estadual de Campinas 2019-01-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2235 10.20396/revpibic2720192235 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 27 (2019): Congresso de Iniciação Científica UNICAMP; 1-1 2596-1969 por https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2235/2286 Copyright (c) 2019 Revista dos Trabalhos de Iniciação Científica da UNICAMP http://creativecommons.org/licenses/by/4.0
spellingShingle Ribeiro, Michelle
Nery, Mariana
Souza, Érica de
Ramos, Elisa
Cetaceans
Migration
Evolutionary genomics
When being obese is healthy: molecular evolution of genes related to metabolism in cetaceans
title When being obese is healthy: molecular evolution of genes related to metabolism in cetaceans
title_full When being obese is healthy: molecular evolution of genes related to metabolism in cetaceans
title_fullStr When being obese is healthy: molecular evolution of genes related to metabolism in cetaceans
title_full_unstemmed When being obese is healthy: molecular evolution of genes related to metabolism in cetaceans
title_short When being obese is healthy: molecular evolution of genes related to metabolism in cetaceans
title_sort when being obese is healthy: molecular evolution of genes related to metabolism in cetaceans
topic Cetaceans
Migration
Evolutionary genomics
url https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2235
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