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In vitro penicillinase activity of ?-lactamase OXA-143(P227S): pH effect

Antibiotic resistance is a global threat. The Class D ?-lactamase OXA-143 has been described as an efficient penicillinase, oxacillinase, and carbapenemase. This Class of enzymes has an unusual lysine (K84) that in the carbamylated form acts as a general base. Recent studies performed in our laborat...

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Bibliographic Details
Main Authors:	Costa, Luiz, Favaro, Denize, Antunes, Víctor
Format:	Online
Language:	Portuguese
Published:	Universidade Estadual de Campinas 2019
Subjects:	Antibiotic resistance Carbapenem-hydrolyzing Class D β-lactamase Enzyme kinetics
Online Access:	https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2296
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