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Characterization and study of the effect of sulfate and bicarbonate on the catalytic activity of ?-lactamase OXA-143 (P227S)

The aim of this study was to determine the hydrodynamic parameters of ?-lactamase OXA-143(P227S) and to evaluate the effect of sulfate and bicarbonate salts on the penicillinase activity of the enzyme. Using chromatographic and spectroscopic techniques, it was possible to determine its diffusion coe...

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Bibliographic Details
Main Authors: Rospendowski, Rafael, Favaro, Denize, Antunes, Víctor
Format: Online
Language:Portuguese
Published: Universidade Estadual de Campinas 2019
Subjects:
Antibiotic resistance
β-lactamase
Enzyme kinetics
Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2601
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