Improving cellobiose utilization and fermentation by Saccharomyces cerevisiae strains via metabolic and evolutionary engineering
Engineered yeast chassis are frequently used for the industrial production of biofuels and chemicals. However, after some initial metabolic engineering steps, further optimization of the microbial host is usually required to achieve high product yields and productivities. In this project, we aim to...
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| Format: | Online |
| Language: | Portuguese |
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Universidade Estadual de Campinas
2019
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| Online Access: | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2989 |
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| author | Lanza, Jennifer Gombert, Andreas Bermejo, Pamela |
| author_facet | Lanza, Jennifer Gombert, Andreas Bermejo, Pamela |
| author_sort | Lanza, Jennifer |
| collection | Portal de Eventos Científicos da UNICAMP |
| container_reference | Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 27 (2019): Congresso de Iniciação Científica UNICAMP; 1-1 |
| description | Engineered yeast chassis are frequently used for the industrial production of biofuels and chemicals. However, after some initial metabolic engineering steps, further optimization of the microbial host is usually required to achieve high product yields and productivities. In this project, we aim to improve the conversion of cellobiose into ethanol by Saccharomyces cerevisiae. For this purpose, we first metabolically engineered cellobiose transporters and intracellular cellobiases into yeast. Subsequently, the engineered strains were subjected to laboratory evolution, in order to improve their growth rates on cellobiose. |
| first_indexed | 2025-10-08T13:59:14Z |
| format | Online |
| id | ojs-article-2989 |
| institution | Universidade Estadual de Campinas |
| issn | 2596-1969 |
| language | por |
| last_indexed | 2025-10-08T13:59:14Z |
| publishDate | 2019 |
| publisher | Universidade Estadual de Campinas |
| record_format | ojs |
| spelling | ojs-article-29892025-09-26T14:39:16Z Improving cellobiose utilization and fermentation by Saccharomyces cerevisiae strains via metabolic and evolutionary engineering Lanza, Jennifer Gombert, Andreas Bermejo, Pamela Saccharomyces cerevisiae Cellobiose Biofuels Engineered yeast chassis are frequently used for the industrial production of biofuels and chemicals. However, after some initial metabolic engineering steps, further optimization of the microbial host is usually required to achieve high product yields and productivities. In this project, we aim to improve the conversion of cellobiose into ethanol by Saccharomyces cerevisiae. For this purpose, we first metabolically engineered cellobiose transporters and intracellular cellobiases into yeast. Subsequently, the engineered strains were subjected to laboratory evolution, in order to improve their growth rates on cellobiose. Universidade Estadual de Campinas 2019-11-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2989 10.20396/revpibic2720192989 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 27 (2019): Congresso de Iniciação Científica UNICAMP; 1-1 2596-1969 por https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2989/2983 Copyright (c) 2019 Revista dos Trabalhos de Iniciação Científica da UNICAMP http://creativecommons.org/licenses/by/4.0 |
| spellingShingle | Lanza, Jennifer Gombert, Andreas Bermejo, Pamela Saccharomyces cerevisiae Cellobiose Biofuels Improving cellobiose utilization and fermentation by Saccharomyces cerevisiae strains via metabolic and evolutionary engineering |
| title | Improving cellobiose utilization and fermentation by Saccharomyces cerevisiae strains via metabolic and evolutionary engineering |
| title_full | Improving cellobiose utilization and fermentation by Saccharomyces cerevisiae strains via metabolic and evolutionary engineering |
| title_fullStr | Improving cellobiose utilization and fermentation by Saccharomyces cerevisiae strains via metabolic and evolutionary engineering |
| title_full_unstemmed | Improving cellobiose utilization and fermentation by Saccharomyces cerevisiae strains via metabolic and evolutionary engineering |
| title_short | Improving cellobiose utilization and fermentation by Saccharomyces cerevisiae strains via metabolic and evolutionary engineering |
| title_sort | improving cellobiose utilization and fermentation by saccharomyces cerevisiae strains via metabolic and evolutionary engineering |
| topic | Saccharomyces cerevisiae Cellobiose Biofuels |
| url | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2989 |
| work_keys_str_mv | AT lanzajennifer improvingcellobioseutilizationandfermentationbysaccharomycescerevisiaestrainsviametabolicandevolutionaryengineering AT gombertandreas improvingcellobioseutilizationandfermentationbysaccharomycescerevisiaestrainsviametabolicandevolutionaryengineering AT bermejopamela improvingcellobioseutilizationandfermentationbysaccharomycescerevisiaestrainsviametabolicandevolutionaryengineering |
