Exploring methodologies to obtain the metabolomic profile of biological fluids by LC/MS-MS

The investigation of methodologies to obtain the metabolomic profile of blood serum from healthy individuals by LCMS/MS was performed by factorial planning and the number of molecular features as the system answer. Sample preparation, chromatographic and ionization source conditions were optimized,...

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Bibliographic Details
Main Authors: Filliettaz, Flavia Presta, Cantu, Ana Valeria Colnaghi Simionato, Duarte, Gustavo H. B., Eberlin, Marcos N., Poppi, Ronei J.
Format: Online
Language:English
Published: Universidade Estadual de Campinas 2019
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Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/454
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Summary:The investigation of methodologies to obtain the metabolomic profile of blood serum from healthy individuals by LCMS/MS was performed by factorial planning and the number of molecular features as the system answer. Sample preparation, chromatographic and ionization source conditions were optimized, defining the best conditions to obtain the metabolomic profile of biofluids to be applied in future identification of potential tumor biomarkers.
ISSN:2596-1969