Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage

The objective of this study was to evaluate the antioxidant potential of lyophilized beet leaves through biochemical tests in the prevention or reduction of LDL oxidation and DNA damage. The results of the present study showed that 100 ppm beet leaf extract protects LDL oxidation 100% and maintained...

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Main Authors: Massa, Gabriel Osti, Bezerra, Rosangela Maria Neves, Silva, Luiz Guilherme S. da, Castro, Ana Paula R. B. de, Simabuco, Fernando M.
Format: Online
Language:English
Published: Universidade Estadual de Campinas 2019
Subjects:
Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/488
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author Massa, Gabriel Osti
Bezerra, Rosangela Maria Neves
Silva, Luiz Guilherme S. da
Castro, Ana Paula R. B. de
Simabuco, Fernando M.
author_facet Massa, Gabriel Osti
Bezerra, Rosangela Maria Neves
Silva, Luiz Guilherme S. da
Castro, Ana Paula R. B. de
Simabuco, Fernando M.
author_sort Massa, Gabriel Osti
collection Portal de Eventos Científicos da UNICAMP
container_reference Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp
description The objective of this study was to evaluate the antioxidant potential of lyophilized beet leaves through biochemical tests in the prevention or reduction of LDL oxidation and DNA damage. The results of the present study showed that 100 ppm beet leaf extract protects LDL oxidation 100% and maintained HUVECs viability in 48 hours when treated whith 1 ppm beet leaf extract and exposed to oxidized LDL. However as for DNA breakage, this protective effect was not observed.
first_indexed 2025-10-08T13:51:00Z
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institution Universidade Estadual de Campinas
issn 2596-1969
language eng
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publishDate 2019
publisher Universidade Estadual de Campinas
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spelling ojs-article-4882025-09-26T14:32:30Z Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage Massa, Gabriel Osti Bezerra, Rosangela Maria Neves Silva, Luiz Guilherme S. da Castro, Ana Paula R. B. de Simabuco, Fernando M. Bioactive compound Beet Reactive oxygen species (ROS). The objective of this study was to evaluate the antioxidant potential of lyophilized beet leaves through biochemical tests in the prevention or reduction of LDL oxidation and DNA damage. The results of the present study showed that 100 ppm beet leaf extract protects LDL oxidation 100% and maintained HUVECs viability in 48 hours when treated whith 1 ppm beet leaf extract and exposed to oxidized LDL. However as for DNA breakage, this protective effect was not observed. Universidade Estadual de Campinas 2019-01-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/488 10.20396/revpibic262018488 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp 2596-1969 eng https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/488/465 Copyright (c) 2019 Gabriel Osti Massa, Rosangela Maria Neves Bezerra http://creativecommons.org/licenses/by/4.0
spellingShingle Massa, Gabriel Osti
Bezerra, Rosangela Maria Neves
Silva, Luiz Guilherme S. da
Castro, Ana Paula R. B. de
Simabuco, Fernando M.
Bioactive compound
Beet
Reactive oxygen species (ROS).
Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage
title Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage
title_full Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage
title_fullStr Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage
title_full_unstemmed Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage
title_short Effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of LDL oxidation and oxidative DNA damage
title_sort effect of bioactive compounds from beet leaf and stem extract on the prevention or reduction of ldl oxidation and oxidative dna damage
topic Bioactive compound
Beet
Reactive oxygen species (ROS).
url https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/488
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