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Advanced microscopy applied to the study of photodynamic mechanism in bacteria

Photodynamic therapy (PDT) is an emergent technique used in clinical treatments for several pathologies, in which the photoactivation of photosensitizer molecule leads to cell death. Our project investigates the photodynamic effect of Protoporphyrin IX (PpIX), one of the currently most used photosen...

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Bibliographic Details
Main Authors: Bertagna, Júlia, Co, Monica Alonso, Munar, Duber M. M., Reis, Edmyr R., Mesquita, Rickson C.
Format: Online
Language:English
Published: Universidade Estadual de Campinas 2019
Subjects:
Photodynamic therapy
Protoporphyrin
Bacteria.
Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/701
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Summary:Photodynamic therapy (PDT) is an emergent technique used in clinical treatments for several pathologies, in which the photoactivation of photosensitizer molecule leads to cell death. Our project investigates the photodynamic effect of Protoporphyrin IX (PpIX), one of the currently most used photosensitizers, in prokaryotic cells, in order to explore its use in sterilization. Atomic Force Microscopy (AFM) and Wide Field Microscopy (WFM) were used to evaluate PDT effects on X.fastidiosa cells.
ISSN:2596-1969

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