Establishment and characterization of a model of Mayaro virus infection in immunocompromised mice

Mayaro virus (MAYV) belongs to the Alphavirus genus along with other important viruses such as Chikungunya virus (CHIKV). The chronic disease caused by MAYV is described by a highly incapacitating joint pain which may endure for several weeks or months in at least 50% of the symptomatic patients. Re...

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Main Authors: Pereira, Alexandre Borin, Marques, Rafael Elias, Coimbra, Laís Durço, Carvalho, Ana Carolina, Consonni, Silvio, Nogueira, Mauricio L.
Format: Online
Language:English
Published: Universidade Estadual de Campinas 2018
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Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/76
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author Pereira, Alexandre Borin
Marques, Rafael Elias
Coimbra, Laís Durço
Carvalho, Ana Carolina
Consonni, Silvio
Nogueira, Mauricio L.
author_facet Pereira, Alexandre Borin
Marques, Rafael Elias
Coimbra, Laís Durço
Carvalho, Ana Carolina
Consonni, Silvio
Nogueira, Mauricio L.
author_sort Pereira, Alexandre Borin
collection Portal de Eventos Científicos da UNICAMP
container_reference Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp
description Mayaro virus (MAYV) belongs to the Alphavirus genus along with other important viruses such as Chikungunya virus (CHIKV). The chronic disease caused by MAYV is described by a highly incapacitating joint pain which may endure for several weeks or months in at least 50% of the symptomatic patients. Recently, reports of sporadic outbreaks in humans has increased, however, the dynamic of the Mayaro infection is not completely understood and there is still no treatment or vaccine available. Herein, our goal was to develop an animal immunocompromised model ideal to understand the immunologic dynamic of the disease and perform antiviral tests.
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spelling ojs-article-762025-09-26T14:32:30Z Establishment and characterization of a model of Mayaro virus infection in immunocompromised mice Pereira, Alexandre Borin Marques, Rafael Elias Coimbra, Laís Durço Carvalho, Ana Carolina Consonni, Silvio Nogueira, Mauricio L. Mayaro virus Animal model Inflammation. Mayaro virus (MAYV) belongs to the Alphavirus genus along with other important viruses such as Chikungunya virus (CHIKV). The chronic disease caused by MAYV is described by a highly incapacitating joint pain which may endure for several weeks or months in at least 50% of the symptomatic patients. Recently, reports of sporadic outbreaks in humans has increased, however, the dynamic of the Mayaro infection is not completely understood and there is still no treatment or vaccine available. Herein, our goal was to develop an animal immunocompromised model ideal to understand the immunologic dynamic of the disease and perform antiviral tests. Universidade Estadual de Campinas 2018-12-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/76 10.20396/revpibic26201876 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp 2596-1969 eng https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/76/72 Copyright (c) 2018 Alexandre Borin Pereira, Rafael Elias Marques http://creativecommons.org/licenses/by/4.0
spellingShingle Pereira, Alexandre Borin
Marques, Rafael Elias
Coimbra, Laís Durço
Carvalho, Ana Carolina
Consonni, Silvio
Nogueira, Mauricio L.
Mayaro virus
Animal model
Inflammation.
Establishment and characterization of a model of Mayaro virus infection in immunocompromised mice
title Establishment and characterization of a model of Mayaro virus infection in immunocompromised mice
title_full Establishment and characterization of a model of Mayaro virus infection in immunocompromised mice
title_fullStr Establishment and characterization of a model of Mayaro virus infection in immunocompromised mice
title_full_unstemmed Establishment and characterization of a model of Mayaro virus infection in immunocompromised mice
title_short Establishment and characterization of a model of Mayaro virus infection in immunocompromised mice
title_sort establishment and characterization of a model of mayaro virus infection in immunocompromised mice
topic Mayaro virus
Animal model
Inflammation.
url https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/76
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