Thermodynamic analysis of Saccharomyces cerevisiae growth: a theoretical-experimental approach

The yeast Saccharomyces cerevisiae is able to oxidize the glucose molecule through the metabolic pathways of fermentation and respiration, storing the released energy in the chemical bonds of the ATP molecule. However, less than half of this energy is used for ATP synthesis, supporting the hypothesi...

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Main Authors: Meirelles, Laura Fernandes de Almeida, Gombert, Andreas Karoly, Filho, Pedro Alcântara Pessôa
Format: Online
Language:English
Published: Universidade Estadual de Campinas 2019
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Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/794
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author Meirelles, Laura Fernandes de Almeida
Gombert, Andreas Karoly
Filho, Pedro Alcântara Pessôa
author_facet Meirelles, Laura Fernandes de Almeida
Gombert, Andreas Karoly
Filho, Pedro Alcântara Pessôa
author_sort Meirelles, Laura Fernandes de Almeida
collection Portal de Eventos Científicos da UNICAMP
container_reference Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp
description The yeast Saccharomyces cerevisiae is able to oxidize the glucose molecule through the metabolic pathways of fermentation and respiration, storing the released energy in the chemical bonds of the ATP molecule. However, less than half of this energy is used for ATP synthesis, supporting the hypothesis that the cell stores the spare energy in the chemical bonds of other components, in addition to releasing some of the energy in the form of heat. To verify this hypothesis, the present work validated a series of analyzes for the determination of the cell's composition, whether in relation to macromolecular and elemental components or metabolites. These analyzes will be applied in bioreactor cultivations under anaerobiosis or under aerobiosis, allowing to evaluate if the composition of the cells varies in these two conditions.
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spelling ojs-article-7942025-09-26T14:32:30Z Thermodynamic analysis of Saccharomyces cerevisiae growth: a theoretical-experimental approach Meirelles, Laura Fernandes de Almeida Gombert, Andreas Karoly Filho, Pedro Alcântara Pessôa Yeast physiology Gibbs energy Saccharomyces cerevisiae. The yeast Saccharomyces cerevisiae is able to oxidize the glucose molecule through the metabolic pathways of fermentation and respiration, storing the released energy in the chemical bonds of the ATP molecule. However, less than half of this energy is used for ATP synthesis, supporting the hypothesis that the cell stores the spare energy in the chemical bonds of other components, in addition to releasing some of the energy in the form of heat. To verify this hypothesis, the present work validated a series of analyzes for the determination of the cell's composition, whether in relation to macromolecular and elemental components or metabolites. These analyzes will be applied in bioreactor cultivations under anaerobiosis or under aerobiosis, allowing to evaluate if the composition of the cells varies in these two conditions. Universidade Estadual de Campinas 2019-01-29 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/794 10.20396/revpibic262018794 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp 2596-1969 eng https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/794/864 Copyright (c) 2019 Laura Fernandes de Almeida Meirelles, Andreas Karoly Gombert http://creativecommons.org/licenses/by/4.0
spellingShingle Meirelles, Laura Fernandes de Almeida
Gombert, Andreas Karoly
Filho, Pedro Alcântara Pessôa
Yeast physiology
Gibbs energy
Saccharomyces cerevisiae.
Thermodynamic analysis of Saccharomyces cerevisiae growth: a theoretical-experimental approach
title Thermodynamic analysis of Saccharomyces cerevisiae growth: a theoretical-experimental approach
title_full Thermodynamic analysis of Saccharomyces cerevisiae growth: a theoretical-experimental approach
title_fullStr Thermodynamic analysis of Saccharomyces cerevisiae growth: a theoretical-experimental approach
title_full_unstemmed Thermodynamic analysis of Saccharomyces cerevisiae growth: a theoretical-experimental approach
title_short Thermodynamic analysis of Saccharomyces cerevisiae growth: a theoretical-experimental approach
title_sort thermodynamic analysis of saccharomyces cerevisiae growth: a theoretical-experimental approach
topic Yeast physiology
Gibbs energy
Saccharomyces cerevisiae.
url https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/794
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AT filhopedroalcantarapessoa thermodynamicanalysisofsaccharomycescerevisiaegrowthatheoreticalexperimentalapproach