Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry
Enteric infections caused by Salmonella spp. represent a major public health problem worldwide, due to the large proportion of foodborne infections derived from this pathogen. Currently, antimicrobials are used to prevent contamination of chicken meat. However, in order to combat salmonellosis witho...
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| Format: | Online |
| Language: | English |
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Universidade Estadual de Campinas
2018
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| Online Access: | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/86 |
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| author | Calarga, Aline Parolin Brocchi, Marcelo |
| author_facet | Calarga, Aline Parolin Brocchi, Marcelo |
| author_sort | Calarga, Aline Parolin |
| collection | Portal de Eventos Científicos da UNICAMP |
| container_reference | Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp |
| description | Enteric infections caused by Salmonella spp. represent a major public health problem worldwide, due to the large proportion of foodborne infections derived from this pathogen. Currently, antimicrobials are used to prevent contamination of chicken meat. However, in order to combat salmonellosis without the propagation of resistant strains, it is necessary to study alternative therapeutic approaches, such as the use of bacteriophages against Salmonellosis. For the present work bacteriophages provided by FMRP-USP were selected to further studies on its therapeutic potential. In addition, we work with lytic bacteriophages induced from monophasic strains of Salmonella spp. Our initial aim for this project was the morphological and molecular characterization of these viruses. Nevertheless, the environmental phages did not survive the storage period. Due to these results, our further studies will be focused on the lytic phages. They will be tested in vivo in the C. elegans model in order to evaluate the survival rate of the worms when infected with Salmonella spp. |
| first_indexed | 2025-10-08T13:49:48Z |
| format | Online |
| id | ojs-article-86 |
| institution | Universidade Estadual de Campinas |
| issn | 2596-1969 |
| language | eng |
| last_indexed | 2025-10-08T13:49:48Z |
| publishDate | 2018 |
| publisher | Universidade Estadual de Campinas |
| record_format | ojs |
| spelling | ojs-article-862025-09-26T14:32:30Z Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry Calarga, Aline Parolin Brocchi, Marcelo Salmonella spp Bacteriophages Poultry. Enteric infections caused by Salmonella spp. represent a major public health problem worldwide, due to the large proportion of foodborne infections derived from this pathogen. Currently, antimicrobials are used to prevent contamination of chicken meat. However, in order to combat salmonellosis without the propagation of resistant strains, it is necessary to study alternative therapeutic approaches, such as the use of bacteriophages against Salmonellosis. For the present work bacteriophages provided by FMRP-USP were selected to further studies on its therapeutic potential. In addition, we work with lytic bacteriophages induced from monophasic strains of Salmonella spp. Our initial aim for this project was the morphological and molecular characterization of these viruses. Nevertheless, the environmental phages did not survive the storage period. Due to these results, our further studies will be focused on the lytic phages. They will be tested in vivo in the C. elegans model in order to evaluate the survival rate of the worms when infected with Salmonella spp. Universidade Estadual de Campinas 2018-12-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/86 10.20396/revpibic26201886 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp 2596-1969 eng https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/86/81 Copyright (c) 2018 Aline Parolin Calarga, Marcelo Brocchi http://creativecommons.org/licenses/by/4.0 |
| spellingShingle | Calarga, Aline Parolin Brocchi, Marcelo Salmonella spp Bacteriophages Poultry. Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry |
| title | Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry |
| title_full | Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry |
| title_fullStr | Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry |
| title_full_unstemmed | Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry |
| title_short | Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry |
| title_sort | genomic analysis and morphological characterization of bacteriophages for salmonella spp. treatment in poultry |
| topic | Salmonella spp Bacteriophages Poultry. |
| url | https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/86 |
| work_keys_str_mv | AT calargaalineparolin genomicanalysisandmorphologicalcharacterizationofbacteriophagesforsalmonellaspptreatmentinpoultry AT brocchimarcelo genomicanalysisandmorphologicalcharacterizationofbacteriophagesforsalmonellaspptreatmentinpoultry |