Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry

Enteric infections caused by Salmonella spp. represent a major public health problem worldwide, due to the large proportion of foodborne infections derived from this pathogen. Currently, antimicrobials are used to prevent contamination of chicken meat. However, in order to combat salmonellosis witho...

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Main Authors: Calarga, Aline Parolin, Brocchi, Marcelo
Format: Online
Language:English
Published: Universidade Estadual de Campinas 2018
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Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/86
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author Calarga, Aline Parolin
Brocchi, Marcelo
author_facet Calarga, Aline Parolin
Brocchi, Marcelo
author_sort Calarga, Aline Parolin
collection Portal de Eventos Científicos da UNICAMP
container_reference Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp
description Enteric infections caused by Salmonella spp. represent a major public health problem worldwide, due to the large proportion of foodborne infections derived from this pathogen. Currently, antimicrobials are used to prevent contamination of chicken meat. However, in order to combat salmonellosis without the propagation of resistant strains, it is necessary to study alternative therapeutic approaches, such as the use of bacteriophages against Salmonellosis. For the present work bacteriophages provided by FMRP-USP were selected to further studies on its therapeutic potential. In addition, we work with lytic bacteriophages induced from monophasic strains of Salmonella spp. Our initial aim for this project was the morphological and molecular characterization of these viruses. Nevertheless, the environmental phages did not survive the storage period. Due to these results, our further studies will be focused on the lytic phages. They will be tested in vivo in the C. elegans model in order to evaluate the survival rate of the worms when infected with Salmonella spp.
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spelling ojs-article-862025-09-26T14:32:30Z Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry Calarga, Aline Parolin Brocchi, Marcelo Salmonella spp Bacteriophages Poultry. Enteric infections caused by Salmonella spp. represent a major public health problem worldwide, due to the large proportion of foodborne infections derived from this pathogen. Currently, antimicrobials are used to prevent contamination of chicken meat. However, in order to combat salmonellosis without the propagation of resistant strains, it is necessary to study alternative therapeutic approaches, such as the use of bacteriophages against Salmonellosis. For the present work bacteriophages provided by FMRP-USP were selected to further studies on its therapeutic potential. In addition, we work with lytic bacteriophages induced from monophasic strains of Salmonella spp. Our initial aim for this project was the morphological and molecular characterization of these viruses. Nevertheless, the environmental phages did not survive the storage period. Due to these results, our further studies will be focused on the lytic phages. They will be tested in vivo in the C. elegans model in order to evaluate the survival rate of the worms when infected with Salmonella spp. Universidade Estadual de Campinas 2018-12-04 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artigo de convidado application/pdf https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/86 10.20396/revpibic26201886 Revista dos Trabalhos de Iniciação Científica da UNICAMP; n. 26 (2018): Congresso de Iniciação Científica Unicamp 2596-1969 eng https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/86/81 Copyright (c) 2018 Aline Parolin Calarga, Marcelo Brocchi http://creativecommons.org/licenses/by/4.0
spellingShingle Calarga, Aline Parolin
Brocchi, Marcelo
Salmonella spp
Bacteriophages
Poultry.
Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry
title Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry
title_full Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry
title_fullStr Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry
title_full_unstemmed Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry
title_short Genomic analysis and morphological characterization of bacteriophages for Salmonella spp. treatment in poultry
title_sort genomic analysis and morphological characterization of bacteriophages for salmonella spp. treatment in poultry
topic Salmonella spp
Bacteriophages
Poultry.
url https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/86
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