Cost-effectiveness analysis of influenza A (H1N1) chemoprophylaxis in unified health system in Brazil

BACKGROUND: Oseltamivir and zanamivir have indication for treating symptomatic flu and in prophylaxis in epidemics for groups with high risk of complications. METHODS: Effectiveness data was identified in literature review, and costs were obtained from official systems and micro-costing. RESULTS: We...

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Bibliographic Details
Main Authors: Vecoso, Luisa Von Zuben, Galvao, Tais Freire, Silva, Marcus, Silva, Everton, Resende, Mariangela
Format: Online
Language:English
Published: Universidade Estadual de Campinas 2019
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Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/926
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Summary:BACKGROUND: Oseltamivir and zanamivir have indication for treating symptomatic flu and in prophylaxis in epidemics for groups with high risk of complications. METHODS: Effectiveness data was identified in literature review, and costs were obtained from official systems and micro-costing. RESULTS: We adopted a decision-tree model to assess the effectiveness of chemoprophylaxis in Brazilian Unified Health System (SUS) perspective with willingness to pay BRL 30,000.00/QALY. The incremental cost-effectiveness ratio for chemoprophylaxis compared to no prophylaxis was - 2,921.14/QALY. CONCLUSION: Chemoprophylaxis is cost-effective in Brazilian scenario.
ISSN:2596-1969