Study of tumour global DNA methylation and mtor pathway genes promoters methylation in maternally leucine-supplemented tumour-bearing adult rats

Cancer-cachexia is a multifactorial syndrome characterised by negative protein balance, associated with alterations in Akt/mTOR (protein synthesis) and Ubiquitin-proteasome (protein degradation) pathways. Maternal supplementation with the amino acid leucine during pregnancy and lactation can amelior...

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Bibliographic Details
Main Authors: Manhe, Beatriz, Marcondes, Maria, Oliveira, Sarah de, Miyaguti, Natália, Geraldo, Murilo, Gomes-Marcondes, Maria
Format: Online
Language:Portuguese
Published: Universidade Estadual de Campinas 2019
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Online Access:https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/2948
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